(FKZ: 031B0963)

• Development of a novel digitized spacer for longitudinal tracking of the infection situation in two-stage total endoprosthesis (TEP) replacement
• Up to 30% (BRD) of patients with joint implants are affected by infections

Main question: When can the spacer interval be terminated and the final endoprosthesis be implanted?

Our Vision:
• Digitalized spacer system, for local, continuous non-invasive and objective measurements (e.g. video images from inside the knee and spectral information)
• Definition of a threshold value (when is the joint considered bug free)
• Elimination of arthroscopies and their risks (anesthesia, embolisms, new infections and trauma)
• Reduction of treatment costs by shortening inpatient treatment

Previous results/References:
• 3D-printed, digitized spacer prototypes with (digit-Spacer; Fig. 1)

• Intra-articular live image and video recordings of ex-vivo knee preparations (porcin, human) (Fig. 2)

• Contribution to „X. Münchener Symposium für experimentelle Orthopädie, Unfallchirurgie und muskuloskelettale Forschung“
• Registered invention disclosure/patent

Details of the funding initiative:
• Go-Bio-initial (BMBF) as a two-stage funding initiative (exploratory/feasibility phase)

Heinz-Nixdorf-Chair of Biomedical Electronics:;;
Clinic for Orthopedics and Sports Orthopedics of the Klinikum rechts der