Single-Cell Analysis
Our research focuses on integrating biosensors, single-cell handling, microfluidics, and immunological targeting in Lab-on-a-chip-based platform technologies for single-cell function testing and extracellular vesicle or protein quantification in complex media.
Group Leader: Moritz Leuthner
Label-free Imaging Cytometry
We combine quantitative phase imaging, microfluidics and image analysis algorithms for biomedical applications. This method requires minimal sample preparation and is used in the medical fields of hematology, oncology and parasitology.
Group Leader: Ellen Emken (ellen.emken@tum.de)
Live Tissue Analysis
The processing and sensor-based, dynamic analysis of live tissues is essential to meet clinical demands both for in-vitro settings (e.g. for diagnostics on explanted human samples) and active implanted devices in vivo. Ideally, this means immediate translation of biomedical engineering developments to improve therapies.
Group Leader: Martin Brischwein (brischwein@tum.de)
CellFACE @ TUM-CREATE Singapore
The Chair leads a team of interdisciplinary (A*Star, MRI, NTU, NUS, NUHS, Sunningdale Ltd, TUM) for the NRF project “CellFACE - Imaging-based Flow Cytometry for Hidden Haematology Biomarker”. Within a clinical study at NUHS, the team will demonstrate the diagnostic opportunities of blood cell interactions currently hidden for the routine diagnostics.
Biomedical Acoustofluidics
Our focus is on the application of label-free fluid and particle manipulation to biomedical sciences for developing novel characterization, diagnostic, and treatment platform technologies. Our special interest is in applying piezo-acoustics and automated microfluidic analyses to enable feedback control systems for pre-clinical and clinical life science tools, in particular to enable a quantitative understanding of organoids and tumors in complex micro-environments.
Group leader: Dr. Shilpi Pandey (shilpi.pandey@tum.de) / Bettina Sailer (bettina.sailer@tum.de)