Label-Free Imaging Flow Cytometry
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CellFACE aims to establish imaging flow cytometry as a label-free platform technology for routine cell function diagnostics, supporting acute care with point-of-care solutions. Back-to-back teams from Munich and Singapore are developing instrument and cartridge prototypes, as well as AI-supported image analysis for on-the-fly analysis.
Discovery of novel biomarkers for early detection of hematological disorders and cancer
Routine diagnosis of hematological disorders requires stained blood smear analysis and remains the gold standard. To overcome the analytical limitations of today’s methods, we combine high-throughput microfluidic systems with digital holographic microscopy for improved early detection and treatment of hematological disorders and leukemia. Thereby, the analysis of cells close to in vivo conditions provides novel insights into cell morphology, function and interaction.
Publications:
Label-free high-throughput leukemia detection by holographic microscopy. Adv. Sci., 2018, 1800761
Contact: Ellen Emken (ellen.emken@tum.de)
Detection of human and veterinary parasites for improved treatment and monitoring
The detection of many human and veterinary blood parasites is still challenging today. With our label-free approach we aim to improve the detection close to in vivo conditions by reducing sample preparation effort and analysis time. By this, the first diagnosis and treatment monitoring of (neglected) parasitic diseases can be significantly improved.
Publications:
Contact: Ellen Emken (ellen.emken@tum.de)